Evaluation of Antimicrobial Effectiveness of Root Canal Sealers Modified with Various Herbal Extracts against Candida Albicans and E Faecalis

Ishan Gupta; Manpreet Kaur; Aruna Kanaparthy; Saswat Satyabrata Nanda; Pavan Kumar Pavagada Sreenivasalu; N Vathsala; Ritasha Bhasin

doi:10.4103/jpbs.jpbs_415_23

Evaluation of Antimicrobial Effectiveness of Root Canal Sealers Modified with Various Herbal Extracts against Candida Albicans and E Faecalis

J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S130-S132. doi: 10.4103/jpbs.jpbs_415_23. Epub 2023 Dec 20.

Authors

Ishan Gupta¹, Manpreet Kaur², Aruna Kanaparthy³, Saswat Satyabrata Nanda⁴, Pavan Kumar Pavagada Sreenivasalu⁵, N Vathsala⁶, Ritasha Bhasin⁷

Affiliations

¹ Specialist Endodontist, Sharjah Specialized Dental Centre (EHS), United Arab Emirates.
² Associate Professor, Department of Oral Pathology, Maharishi Markandeshwar College of Dental Sciences and Research (Deemed to be University) Mullana, Haryana, India.
³ Professor, Department of Conservative Dentistry and Endodontics, College of Dental Sciences & Hospital, Amargadh, Gujarat, India.
⁴ Reader, Department of Conservative Dentistry, Institute of Dental Sciences, Shampur, Bhubaneswar, Odisha, India.
⁵ Assistant Professor, Department of Restorative Dental Sciences, College of Dentistry, King Faisal University, PO Box 400, Al Asha-31982, Kingdom of Saudi Arabia.
⁶ Professor, Department of Conservative Dentistry & Endodontics, RVS Dental College & Hospital, Coimbatore, Tamil Nadu, India.
⁷ BDS, DDS, Private Practice, Toronto, Canada.

Abstract

Objectives: The aim of the study was to assess the effectiveness of ZOE-based, calcium hydroxide, and epoxy resin-based sealers on modification with three herbal extracts.

Materials and methods: Methanolic extracts of selected herbs were combined with ZOE-based, calcium hydroxide, and epoxy resin-based sealers. Cultures were prepared from E. faecalis and C. albicans and agar plates prepared. Prepared mixtures were inoculated in punched holes, and inhibitory zones were measured.

Results: No statistical significance was obtained on comparing mean scores of test groups.

Conclusion: None of the combinations used was found to be significantly better than others.

Keywords: Black seed; C. albicans; E faecalis; Glycyrrhiza glabra; Tinospora cordifolia; ZOE-based sealer; calcium hydroxide sealer; epoxy resin-based sealer.