The Efficacy of Platelet-Rich Plasma as an Adjunct to Bone Grafting in Alveolar Ridge Preservation Following Tooth Extraction

Hiroj S Bagde; Mohammad K Alam; Yazan Eid Muteb Almohammed; Sufyan Mohammed Mukhlef Almaqawid; Abdulelah Waheed Noman Alanazi; Fawaz Talal F Alanazi; Mohammed G Sghaireen

doi:10.4103/jpbs.jpbs_865_23

The Efficacy of Platelet-Rich Plasma as an Adjunct to Bone Grafting in Alveolar Ridge Preservation Following Tooth Extraction

J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S564-S566. doi: 10.4103/jpbs.jpbs_865_23. Epub 2024 Feb 29.

Authors

Hiroj S Bagde¹, Mohammad K Alam^{2

3

4}, Yazan Eid Muteb Almohammed², Sufyan Mohammed Mukhlef Almaqawid², Abdulelah Waheed Noman Alanazi², Fawaz Talal F Alanazi², Mohammed G Sghaireen⁵

Affiliations

¹ Professor, Department of Periodontology, CDCRI, Rajnandgaon, Chhattisgarh, India.
² Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.
³ Department of Dental Research Cell, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.
⁴ Department of Public Health, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, Bangladesh.
⁵ Department of Prosthetic Dentistry, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.

Abstract

Background: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss. Platelet-rich plasma (PRP) has been proposed as an adjunct to bone grafting in ARP to enhance bone regeneration.

Materials and methods: A total of 60 patients requiring tooth extraction and ARP were included in this randomized controlled trial. Patients were divided into two groups: Group A received bone grafting alone, while Group B received bone grafting with PRP. Clinical and radiographic assessments were performed at baseline and 6-month postsurgery. Bone density and height were measured using arbitrary values.

Results: At the 6-month follow-up, Group B demonstrated a statistically significant increase in bone density (P < 0.05) and bone height (P < 0.05) compared to Group A. The arbitrary values for bone density in Group B increased by 15% and bone height increased by 10% compared to baseline measurements. Group A showed minimal improvement.

Conclusion: The incorporation of PRP as an adjunct to bone grafting in ARP following tooth extraction significantly enhances bone density and height, suggesting its efficacy in preserving the alveolar ridge.

Keywords: Alveolar ridge preservation; bone grafting; dental implants; efficacy; platelet-rich plasma; tooth extraction.