Post-CT-guided lung biopsy optimisation of the observation period by identifying patients at risk of delayed pneumothorax

Samantha Tan; Murray Di Loreto; Stephen Melsom; Reece Jefferies; Christopher Padgham; Glenn Boardman; Bann Saffar

doi:10.1111/1754-9485.13646

Post-CT-guided lung biopsy optimisation of the observation period by identifying patients at risk of delayed pneumothorax

J Med Imaging Radiat Oncol. 2024 Apr 9. doi: 10.1111/1754-9485.13646. Online ahead of print.

Authors

Samantha Tan¹, Murray Di Loreto¹, Stephen Melsom¹, Reece Jefferies², Christopher Padgham³, Glenn Boardman⁴, Bann Saffar¹

Affiliations

¹ Medical Imaging Department, Fiona Stanley Hospital, Perth, Western Australia, Australia.
² Department of Respiratory Medicine, Fiona Stanley Hospital, Perth, Western Australia, Australia.
³ Department of Respiratory Medicine, Logan Hospital, QLD Health, Meadowbrook, Queensland, Australia.
⁴ South Metropolitan Health Service, Perth, Western Australia, Australia.

PMID: 38591166
DOI: 10.1111/1754-9485.13646

Abstract

Introduction: Identify the risk factors for delayed pneumothorax after lung biopsy.

Methods: A retrospective study of 355 CT-guided lung biopsies was performed at Fiona Stanley Hospital, Western Australia over 42 months. A comprehensive range of patient, lesion and procedural variables were recorded. All post-procedural complications including time, size of pneumothorax and post-biopsy radiographs were reviewed. Lasso logistic regression model was utilised to determine factors predicting patient complications.

Results: A total of 167 patients (47%) developed a pneumothorax, in which 34% were significant, requiring longer observation or drain insertion. The majority of pneumothoraces occurred within the first hour (86%), with 90% detected at the time of the procedure. Then, 12% were detected more than 3 h post-procedure, of which 8 patients (5%) had a significant delayed pneumothorax. Factors increasing the likelihood of significant pneumothorax include the length of lung traversed, smaller nodule size, surrounding emphysema, increased age and lateral patient position with the lesion in the non-dependent aspect. Increasing patient age, longer length of lung traversed and smaller nodule diameter increase the risk of delayed onset of pneumothorax (more than 3 h).

Conclusion: The results of this study align with other studies indicating it is safe to discharge stable patients within an hour post-lung biopsy. However, specific risk factors, including age, small lesion size and deep lesions, may identify patients who could benefit from a longer observation period.

Keywords: biopsy; computed tomography; image‐guided; lung; thoracic imaging.