Hymenoptera Venom Immunotherapy Meets Factitious Disorder

Cureus. 2024 Mar 8;16(3):e55769. doi: 10.7759/cureus.55769. eCollection 2024 Mar.

Abstract

Factitious disorder on self is a psychiatric disorder in which individuals fabricate or induce signs or symptoms of a disease. Factitious anaphylaxis, with symptoms suggestive of a life-threatening allergic reaction, is extremely rare. Several cases of factitious disorder reactions during allergen immunotherapy for airborne allergens have been reported. We report the case of a young female patient who presented factitious anaphylaxis during venom immunotherapy to vespid venom extract. Symptoms of stridor, dyspnea, coughing and loss of consciousness were observed during the built-up phase of venom immunotherapy, mimicking allergic reactions to the venom extracts. Diagnosis of factitious disorder prompted the discontinuation of venom immunotherapy.

Keywords: allergen-specific immunotherapy (ait); allergic asthma; factitious disorder; insect venom allergy; placebo mechanism; venom immunotherapy.

Publication types

  • Case Reports