Recent trends in extraction, purification, structural characterization, and biological activities evaluation of Perilla frutescens (L.) Britton polysaccharide

Ling Zhu; Lijun Guan; Kunlun Wang; Chuanying Ren; Yang Gao; Jialei Li; Song Yan; Xindi Zhang; Xinmiao Yao; Ye Zhou; Bo Li; Shuwen Lu

doi:10.3389/fnut.2024.1359813

Recent trends in extraction, purification, structural characterization, and biological activities evaluation of Perilla frutescens (L.) Britton polysaccharide

Front Nutr. 2024 Feb 22:11:1359813. doi: 10.3389/fnut.2024.1359813. eCollection 2024.

Authors

Ling Zhu^{1

2}, Lijun Guan^{1

2}, Kunlun Wang^{1

2}, Chuanying Ren^{1

2}, Yang Gao^{1

2}, Jialei Li^{1

2}, Song Yan^{1

2}, Xindi Zhang^{1

2}, Xinmiao Yao^{1

2}, Ye Zhou^{1

2}, Bo Li^{1

2}, Shuwen Lu²

Affiliations

¹ Institute of Food Processing, Heilongjiang Province Academy of Agricultural Sciences, Harbin, China.
² Heilongjiang Province Key Laboratory of Food Processing, Harbin, China.

Abstract

Perilla frutescens (L.) Britton is an annual herb plant of the Perilla genus in the Labiatae family, which is commonly utilized as an edible and medicinal resource. Polysaccharides are among the major components and essential bioactive compounds of P. frutescens, which exhibit a multitude of biological activities, including antioxidant, antitumor, anti-fatigue, immunoregulation, hepatoprotective, anti-inflammatory, and lipid-lowering effects. As a natural carbohydrate, P. frutescens polysaccharide has the potential to be utilized in the development of drugs and functional materials. In this paper, we provide an overview of progress made on the extraction, purification, structural characterization, and bioactivity of polysaccharides from different parts of P. frutescens. The challenges and opportunities for research are discussed, along with the potential development prospects and future areas of focus in the study of P. frutescens polysaccharides.

Keywords: Perilla frutescens; bioactivities; extraction; polysaccharides; structural characterization.

Publication types

Review

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the National Key Research and Development Program of China (2021YFD2100902) and the Agricultural Science and Technology Innovation Project of Heilongjiang Academy of Agricultural Sciences (CX23GG16-04).