Detection and application of hypochlorous acid in both aqueous environments and living organisms

Spectrochim Acta A Mol Biomol Spectrosc. 2024 Jun 5:314:124225. doi: 10.1016/j.saa.2024.124225. Epub 2024 Apr 3.

Abstract

The scarcity of water resources has raised concerns regarding drinking water safety. Excessive addition of hypochlorous acid (OCl-) as a disinfectant in drinking water can result in severe consequences. Moreover, abnormal levels of OCl- within the human body can lead to various diseases. Employing fluorescence analysis, the design and synthesis of specific fluorescent probes for simultaneous detection of OCl- in water environments and living organisms holds strategic significance in ensuring the safety of drinking water and mitigating potential risks caused by its abnormal concentrations. This article utilizes naphthalimide as a precursor to develop a novel probe enabling highly sensitive detection of OCl- in water environments and at the organelle level within living organisms. This endeavor serves to provide assurance for drinking water safety and offers health alerts.

Keywords: Fluorescent; Hypochlorous acid; Naphthalimide; Organelle; Water environment.

MeSH terms

  • Drinking Water* / analysis
  • Fluorescent Dyes
  • Humans
  • Hypochlorous Acid* / analysis

Substances

  • Hypochlorous Acid
  • Drinking Water
  • Fluorescent Dyes