A case series of thyroid fine needle aspiration biopsies diagnosed as follicular neoplasm with oncocytic features

Diagn Cytopathol. 2024 Apr 6. doi: 10.1002/dc.25314. Online ahead of print.

Abstract

Oncocytic lesions of the thyroid are a heterogeneous group encompassing nonneoplastic and neoplastic entities ranging from benign to malignant and have traditionally been classified as separate entities in thyroid pathology. To illustrate the diversity of these thyroid lesions, we describe three cases of fine needle aspiration biopsies (FNAB) diagnosed as Bethesda Category IV: Follicular neoplasm, oncocytic type, under the 2017 Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), with ThyroSeq v3 molecular testing and subsequent surgical excision.

Keywords: Hürthle cell neoplasm; fine needle aspiration biopsy; follicular neoplasm; oncocytic features; thyroid.

Publication types

  • Review