Correct illustration of assumptions in Mendelian randomization

Int J Epidemiol. 2024 Feb 14;53(2):dyae050. doi: 10.1093/ije/dyae050.

Authors

Alice R Carter¹, Emma L Anderson²

Affiliations

¹ Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.
² Division of Psychiatry, Department of Mental Health of Older People, University College London, London, UK.

PMID: 38580457
DOI: 10.1093/ije/dyae050

No abstract available

Keywords: Mendelian randomization; assortative mating; assumptions; independence assumption; instrumental variable; population stratification.

MeSH terms

Genetic Variation*
Humans
Mendelian Randomization Analysis*
Risk Factors

Grants and funding

MR/W011581/1/UKRI Future Leaders Fellowship