Gender differences in the impact of anatomical factors on non-contact anterior cruciate ligament injuries: a magnetic resonance study

BMC Musculoskelet Disord. 2024 Apr 4;25(1):264. doi: 10.1186/s12891-024-07390-5.

Abstract

Purpose: To identify MRI-detected anatomical risk factors for non-contact anterior cruciate ligament (ACL) injuries across genders.

Methods: A retrospective analysis was performed on 141 ACL-reconstructed patients (35 females, 106 males) and 142 controls (37 females, 105 males) from January 2020 to April 2022. Inclusion criteria were primary non-contact ACL injuries. The tibial plateau slope, lateral femoral condyle index, Insall-Salvati index, and patellar tendon angle were measured, using binary logistic regression for gender-specific risk evaluation.

Results: Increased lateral tibial plateau slope, reduced intercondylar notch width index, lateral femoral condyle index, and patellar tendon angle correlated with ACL injuries in both genders. The Insall-Salvati index was a significant risk factor in females but not in males.

Conclusion: This study identifies the lateral tibial plateau slope, notch width index, lateral femoral condyle index, and patellar tendon angle at near-extension as risk factors for ACL injuries in both genders, with the Insall-Salvati index also implicated in females.

Keywords: ACL injury; Gender differences; MRI; Risk factors; Tibiofemoral anatomy.

MeSH terms

  • Anterior Cruciate Ligament Injuries* / diagnostic imaging
  • Anterior Cruciate Ligament Injuries* / etiology
  • Female
  • Humans
  • Knee Joint / diagnostic imaging
  • Magnetic Resonance Imaging / adverse effects
  • Magnetic Resonance Spectroscopy
  • Male
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Tibia