Occurrence and distribution of antibiotics and antibiotic resistance genes from the land to ocean in Daliao River-Liaodong Bay, China

Yunfeng Xu; Hui Gao; Ruijing Li; Yingbin Lou; Bing Li; Guanjie Cheng; Guangshui Na

doi:10.1016/j.marenvres.2024.106470

Occurrence and distribution of antibiotics and antibiotic resistance genes from the land to ocean in Daliao River-Liaodong Bay, China

Mar Environ Res. 2024 May:197:106470. doi: 10.1016/j.marenvres.2024.106470. Epub 2024 Mar 30.

Authors

Yunfeng Xu¹, Hui Gao², Ruijing Li³, Yingbin Lou⁴, Bing Li⁵, Guanjie Cheng⁵, Guangshui Na⁶

Affiliations

¹ College of Marine Ecology and Environment, Shanghai Ocean University, Shanghai, 201306, China; National Marine Environmental Monitoring Center, Dalian, 116023, China.
² National Marine Environmental Monitoring Center, Dalian, 116023, China; College of Marine Technology and Environment, Dalian Ocean University, Dalian, 116023, China. Electronic address: hgao@nmemc.org.cn.
³ National Marine Environmental Monitoring Center, Dalian, 116023, China.
⁴ Dalian Ecological Environment Monitoring Center, Liaoning Province, Dalian, 116023, China.
⁵ National Marine Environmental Monitoring Center, Dalian, 116023, China; College of Marine Technology and Environment, Dalian Ocean University, Dalian, 116023, China.
⁶ College of Marine Ecology and Environment, Shanghai Ocean University, Shanghai, 201306, China; National Marine Environmental Monitoring Center, Dalian, 116023, China; Hainan Key Laboratory for Coastal Marine Eco-environment and Carbon Sink/Yazhou Bay Innovation Institute/College of Ecology and Environment, Hainan Tropical Ocean University, Sanya, 572022, China. Electronic address: nags@hntou.edu.cn.

PMID: 38574497
DOI: 10.1016/j.marenvres.2024.106470

Abstract

In this study, the pollution status of antibiotics and ARGs in sediments from the land-sea intersection of Liaodong Bay was analyzed. The results showed that the level of antibiotic pollution ranged from ND to 433.27 ng/kg, with quinolones and tetracycline as the dominant antibiotics. The relative abundance of ARGs ranged from 3.62 × 10^-3 to 1.32 × 10^-1 copies/16SrRNA copies, with aminoglycoside and MLSB resistance genes being dominant. Regarding spatial distribution, the land and estuary areas showed higher antibiotic pollution levels than the offshore areas. Similarly, the land and estuary areas exhibited higher antibiotic diversity than the offshore areas. The ARGs were widely distributed on land, and their abundance gradually decreased to the downstream estuary area. Land and coastal areas exhibited higher ARG diversity than estuary areas. Analysis of environmental factors revealed a significant correlation between ARGs and non-corresponding antibiotics, and some ARGs were affected by heavy metals Cu and Pb.

Keywords: Antibiotics; Antibiotics resistance genes; DaLiao River - LiaoDong Bay; Environmental factor; Occurrence.

Publication types

Review

MeSH terms

Anti-Bacterial Agents*
Bays*
China
Drug Resistance, Microbial / genetics
Environmental Monitoring / methods
Genes, Bacterial

Substances

Anti-Bacterial Agents