Fog harvesting relies on intercepting atmospheric or industrial fog by placing a porous obstacle, for example, a mesh and collecting the deposited water. In the face of global water scarcity, such fog harvesting has emerged as a viable alternative source of potable water. Typical fog harvesting meshes suffer from poor collection efficiency due to aerodynamic bypassing of the oncoming fog stream and poor collection of the deposited water from the mesh. One pestering challenge in this context is the frequent clogging up of mesh pores by the deposited fog water, which not only yields low drainage efficiency but also generates high aerodynamic resistance to the oncoming fog stream, thereby negatively impacting the fog collection efficiency. Minimizing the clogging is possible by rendering the mesh fibers superhydrophobic, but that entails other detrimental effects like premature dripping and flow-induced re-entrainment of water droplets into the fog stream from the mesh fiber. Herein, we improvise on traditional interweaved metal mesh designs by defining critical parameters, viz., mesh pitch, shade coefficient, and fiber wettability, and deducing their optimal values from numerically and experimentally observed morphology of collected fog water droplets under various operating scenarios. We extend our investigations over a varying range of mesh-wettability, including superhydrophilic and hydrophobic fibers, and go on to find optimal shade coefficients which would theoretically render clog-proof fog harvesting meshes. The aerodynamic, deposition, and overall collection efficiencies are characterized. Hydrophobic meshes with square pores, having fiber diameters smaller than the capillary length scale of water, and an optimal shade coefficient are found to be the most effective design of such clog-proof meshes.