Linear Amine-Linked Oligo-BODIPYs: Convergent Access via Buchwald-Hartwig Coupling

Org Lett. 2024 Apr 19;26(15):3020-3025. doi: 10.1021/acs.orglett.4c00827. Epub 2024 Apr 2.

Abstract

A convergent route toward nitrogen-bridged BODIPY oligomers has been developed. The synthetic key step is a Buchwald-Hartwig cross-coupling reaction of an α-amino-BODIPY and the respective halide. Not only does the selective synthesis provide control of the oligomer size, but the facile preparative procedure also enables easy access to these types of dyes. Furthermore, functionalized examples were accessible via brominated derivatives.