Aortogenic calcified cerebral embolism diagnosed with an embolus retrieved by thrombectomy: illustrative case

J Neurosurg Case Lessons. 2024 Apr 1;7(14):CASE2499. doi: 10.3171/CASE2499. Print 2024 Apr 1.

Abstract

Background: Calcified cerebral embolism has been reported as a cause of acute cerebral infarction, but an aortogenic origin has rarely been identified as the embolic source. The authors describe a case of aortogenic calcified cerebral embolism in a patient with other embolic sources.

Observations: In a patient with cerebral infarction and atrial fibrillation, a white hard embolus was retrieved by mechanical thrombectomy. Pathological analysis of the embolus revealed that it was mostly calcified, with some foam cells and giant cells. The macroscopic and pathological findings allowed the authors to finally diagnose an aortogenic calcified cerebral embolism.

Lessons: Even in patients with cardiogenic embolic sources, it is possible to identify a complex aortic atheroma with calcification as the embolic source, based on the macroscopic and pathological findings of the embolus retrieved by mechanical thrombectomy.

Keywords: aortogenic embolus; calcified cerebral embolus; macroscopic finding; pathology; thrombectomy.