α-Tocopherol: New Perspectives and Challenges for Achieving the Sustainable Development Goals (SDG) Target

J Oleo Sci. 2024;73(4):519-538. doi: 10.5650/jos.ess23199.

Abstract

Vitamin E (VE) is a lipophilic vitamin, and Evans and Bishop demonstrated the existence of a hitherto unrecognized dietary factor essential for normal reproduction in rat. During 100 years after the discovery, α-tocopherol (α-Toc) has been the representative species in VE homologues, and both naturally occurring and synthetically prepared α-Toc have been widely used and studied. Although it is indicated by a single-word VE, research on VE involves various chemical species. It is important to understand the fine structure and accurate characteristics of individual VE species when using VE. Each VE sample has compositional and/or isomer issues, and furthermore, the usability greatly varies depending on the modified species of esterification. The VE industry involves many interdisciplinary fields. Improvements in formulation technology and confirmation of the novel biological activity of VE greatly owns its utility and opens up new applications. As the interim period between the start and end of the agenda for Sustainable Development Goals (SDGs), in this minireview, the recent trends and future guidelines of VE, especially α- Toc, in relation to the SDGs have been demonstrated.

Keywords: SDGs; antioxidant; ferroptosis; formulation; tocopherol; vitamin E.

MeSH terms

  • Animals
  • Isomerism
  • Rats
  • Sustainable Development*
  • Vitamin E
  • Vitamins
  • alpha-Tocopherol*

Substances

  • alpha-Tocopherol
  • Vitamin E
  • Vitamins