Extensive Hepatic Infarction due to Polycythemia Vera

J Gastrointestin Liver Dis. 2024 Mar 29;33(1):18. doi: 10.15403/jgld-5379.

Abstract

Polycythemia vera (PV) is one of the three BCR-ABL1-negative myeloproliferative neoplasms characterized by activating mutations in JAK2, which clinically presents as erythrocytosis and has an increased risk of both thromboembolic events and progression to myelofibrosis and acute myeloid leukemia. Splanchnic vein thrombosis is a rare manifestation of venous thromboembolism involving one or more abdominal vessels and is strongly associated with PV. We herein report a case in which hepatic infarction due to PV was saved by conservative treatment.

Publication types

  • Case Reports

MeSH terms

  • Hepatic Infarction*
  • Humans
  • Polycythemia Vera* / complications
  • Polycythemia Vera* / diagnosis
  • Polycythemia Vera* / genetics
  • Primary Myelofibrosis* / complications
  • Primary Myelofibrosis* / genetics
  • Venous Thrombosis* / diagnostic imaging
  • Venous Thrombosis* / etiology
  • Venous Thrombosis* / therapy