Granulomatous Amyloid Angiopathy in a Patient With Persistent Headache

Cureus. 2024 Feb 27;16(2):e55071. doi: 10.7759/cureus.55071. eCollection 2024 Feb.

Abstract

Cerebral amyloid angiopathy (CAA) is a type of cerebrovascular disorder characterized by the accumulation of amyloid beta peptide within the walls of small to medium-sized blood vessels in the brain and leptomeninges. This can cause a variety of symptoms, depending on the location and extent of the deposits. Common presentations of amyloid angiopathy include cognitive decline, memory loss, headaches, vision changes, stroke-like symptoms, and seizures. In some cases, there may be no noticeable symptoms. A 78-year-old female was admitted for ongoing evaluation of a persistent headache after her primary care physician (PCP) ordered outpatient magnetic resonance imaging (MRI) that showed findings concerning metastatic tumors versus infectious processes. She underwent a right temporal lobe biopsy, which confirmed the diagnosis of granulomatous amyloid angiopathy.

Keywords: age-related disease; cerebral amyloid angiopathy; cerebrospinal fluid studies; hemorrhage - cerebral; s: biomarkers.

Publication types

  • Case Reports