Testicular metastasis from urothelial carcinoma: case report and literature review

Changxue Liu; Jing Liu; Qingbo Yang; Leilei Song; Xiaocheng Ma; Yonghua Wang

doi:10.3389/fonc.2024.1308399

Testicular metastasis from urothelial carcinoma: case report and literature review

Front Oncol. 2024 Mar 14:14:1308399. doi: 10.3389/fonc.2024.1308399. eCollection 2024.

Authors

Changxue Liu¹, Jing Liu², Qingbo Yang¹, Leilei Song³, Xiaocheng Ma¹, Yonghua Wang^{1

4}

Affiliations

¹ Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
² Department of Research Management and International Cooperation, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
³ Department of Operating Room, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
⁴ General Office, Urinary Diseases Clinical Medical Research Center of Qingdao, Qingdao, Shandong, China.

Abstract

Urothelial carcinoma (UC) with testicular metastasis is extremely rare, and its modes of metastasis, prognosis, and treatment are unclear. In this report, we present an extraordinarily rare case of testicular metastasis arising from UC 8 years after surgery. The patient underwent left orchiepididymectomy and received immunotherapy postoperatively. After a 6-month follow-up, there were no signs of recurrence. Moreover, the clinical characteristics, metastasis pattern, and treatment plan were also summarized based on 14 earlier reported cases of UC with testicular metastasis.

Keywords: case report; chemotherapy; immunotherapy; metastasis; testis; urothelial carcinoma.

Publication types

Case Reports

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the National Natural Science Foundation of China (nos. 81972378 and 81101932).