Construction of a nomogram model for deep vein thrombosis in patients with tibial plateau fracture based on the Systemic Inflammatory Response Index

BMC Musculoskelet Disord. 2024 Mar 27;25(1):240. doi: 10.1186/s12891-024-07328-x.

Abstract

Background: In recent years, the incidence of tibial plateau fracture has been on the rise, predominantly affecting the elderly population. Deep vein thrombosis may lead to poor prognosis in patients. the Systemic Inflammatory Response Index are novel biomarkers of inflammation, and this study aims to verify their predictive effect and construct the nomogram model.

Method: This study used binary logistic regression analysis to predict the predictive effect of SIRI on the occurrence of DVT in tibial plateau fracture patients. And use R studio to construct nomogram model.

Result: The results showed that NC (7.036 [3.516, 14.080], p < 0.001), LYM (0.507 [0.265, 0.969], p = 0.04), and SIRI (2.090 [1.044, 4.182], p = 0.037) were independent predictive factors for DVT. The nomogram demonstrated good predictive performance with small errors in both the training and validation groups, and most clinical patients could benefit from them.

Conclusion: The nomogram constructed based on SIRI can assist clinicians in early assessment of the probability of DVT occurrence.

Keywords: Deep vein thrombosis; Nomogram; Systemic Inflammatory Response Index; Tibial plateau fracture.

MeSH terms

  • Aged
  • Humans
  • Inflammation / epidemiology
  • Nomograms
  • Retrospective Studies
  • Systemic Inflammatory Response Syndrome
  • Tibial Fractures* / complications
  • Tibial Fractures* / epidemiology
  • Tibial Plateau Fractures*
  • Venous Thrombosis* / epidemiology
  • Venous Thrombosis* / etiology