Osteoradionecrosis in a Torus Mandibularis Treated by Antimicrobial Photodynamic Therapy: A Case Report

Photobiomodul Photomed Laser Surg. 2024 Apr;42(4):321-323. doi: 10.1089/photob.2023.0173. Epub 2024 Mar 27.

Abstract

Background: Osteoradionecrosis (ORN) of the jaws is a late complication after radiotherapy to head and neck cancer. Objective: To describe a rare case of ORN of the torus mandibularis that was successfully managed exclusively with antimicrobial photodynamic therapy (aPDT). Case report: A 72-year-old man presented an exposed necrotic bone observed in the torus mandibularis, extending to the lingual alveolar ridge with no edema nor suppuration. The treatment provided a noninvasive treatment leading to spontaneous sequestrectomy of the torus in 2 weeks with complete mucosal repair in 5 weeks and absence of lesion signs and/or symptoms even after 6 months of follow-up. Conclusions: The aPDT indicated to be a satisfactory treatment for ORN affecting torus mandibularis, a region with surgical limitations, avoiding surgery.

Keywords: antimicrobial photodynamic therapy; low-power laser; osteoradionecrosis; torus mandibularis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Male
  • Mandibular Diseases / drug therapy
  • Mandibular Diseases / etiology
  • Mandibular Diseases / therapy
  • Osteoradionecrosis* / drug therapy
  • Osteoradionecrosis* / etiology
  • Osteoradionecrosis* / therapy
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use

Substances

  • Photosensitizing Agents