Wound Repair and Ca2+ Signalling Interplay: The Role of Ca2+ Channels in Skin

Cells. 2024 Mar 11;13(6):491. doi: 10.3390/cells13060491.

Abstract

The process of wound healing is intricate and tightly controlled, involving a number of different cellular and molecular processes. Numerous cellular functions, especially those related to wound healing, depend critically on calcium ions (Ca2+). Ca2+ channels are proteins involved in signal transduction and communication inside cells that allow calcium ions to pass through cell membranes. Key Ca2+ channel types involved in wound repair are described in this review.

Keywords: Ca2+; Ca2+ channels; Ca2+ signalling; wound repair.

Publication types

  • Review

MeSH terms

  • Calcium* / metabolism
  • Cell Membrane / metabolism
  • Ions
  • Signal Transduction* / physiology
  • Wound Healing

Substances

  • Calcium
  • Ions