Case Report: Itraconazole Oral Solution Continuous Therapy for Infantile Tinea Capitis

Am J Trop Med Hyg. 2024 Mar 26;110(5):965-967. doi: 10.4269/ajtmh.23-0741. Print 2024 May 1.

Abstract

Tinea capitis is a common fungal infection caused by dermatophytes in children, but it is rare in infants. Although oral itraconazole has been widely used to treat tinea capitis, its use in infants is limited due to its low prevalence in this age group. A previous study reported the effectiveness of itraconazole continuous therapy in treating infantile tinea capitis caused by Microsporum canis. However, this approach has not been extended to tinea capitis caused by other fungi. In this study, we present four cases of infantile tinea capitis treated with continuous itraconazole oral solution therapy (5 mg/kg/day). Two patients were infected with M. canis, one patient with Nannizzia gypsea, and another with Trichophyton tonsurans. This study assesses the efficacy and safety of itraconazole oral solution continuous therapy, expanding our understanding by demonstrating its effectiveness for infantile tinea capitis caused by T. tonsurans and N. gypsea.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Antifungal Agents* / administration & dosage
  • Antifungal Agents* / therapeutic use
  • Female
  • Humans
  • Infant
  • Itraconazole* / administration & dosage
  • Itraconazole* / therapeutic use
  • Male
  • Microsporum / drug effects
  • Tinea Capitis* / drug therapy
  • Tinea Capitis* / microbiology
  • Treatment Outcome

Substances

  • Itraconazole
  • Antifungal Agents

Supplementary concepts

  • Microsporum canis