We isolated Issyk-Kul virus (ISKV) from a bat sampled from Italy in 2021 and conducted ISKV-specific surveillance in bats collected in Italy during 2017-2023. ISKV circulation among synanthropic and sedentary species of bat, such as Savi's pipistrelle bat (Hypsugo savii) in northern Italy, may have public health implications in this region.
Keywords: Hypsugo savii; Issyk-kul virus; Italy; Orthonairovirus; bats; vector-borne infections; viruses; zoonosis.