Sucrose-fermenting Salmonella Typhimurium N23-2364: a challenge for the diagnostic laboratory

Marc J A Stevens; Magdalena Nüesch-Inderbinen; Jule Anna Horlbog; Andrea Diethelm; Roger Stephan

doi:10.1016/j.diagmicrobio.2024.116280

Sucrose-fermenting Salmonella Typhimurium N23-2364: a challenge for the diagnostic laboratory

Diagn Microbiol Infect Dis. 2024 Jun;109(2):116280. doi: 10.1016/j.diagmicrobio.2024.116280. Epub 2024 Mar 20.

Authors

Marc J A Stevens¹, Magdalena Nüesch-Inderbinen², Jule Anna Horlbog², Andrea Diethelm², Roger Stephan³

Affiliations

¹ Vetsuisse Faculty, Institute for Food Safety and Hygiene, University of Zurich, Winterthurerstrasse 272, Zurich CH-8057, Switzerland.
² Vetsuisse Faculty, Institute for Food Safety and Hygiene, University of Zurich, Winterthurerstrasse 272, Zurich CH-8057, Switzerland; Swiss National Reference Centre for Enteropathogenic Bacteria and Listeria, Switzerland.
³ Vetsuisse Faculty, Institute for Food Safety and Hygiene, University of Zurich, Winterthurerstrasse 272, Zurich CH-8057, Switzerland. Electronic address: roger.stephan@uzh.ch.

PMID: 38522369
DOI: 10.1016/j.diagmicrobio.2024.116280

Abstract

We describe a case of Salmonella infection caused by a sucrose-fermenting Salmonella enterica Typhimurium sequence type 12 which acquired transposon CTnscr94 carrying the sucrose operon scrKYABR. Sucrose-fermenting Salmonella are particularly challenging for culture-based detection and may lead to failure to detect Salmonella in clinical samples.

Keywords: Salmonella Typhimurium ST12; Sucrose-fermenting Salmonella; suc operon.

Publication types

Case Reports

MeSH terms

DNA Transposable Elements / genetics
Fermentation
Humans
Male
Operon
Salmonella Infections* / diagnosis
Salmonella Infections* / microbiology
Salmonella typhimurium* / genetics
Salmonella typhimurium* / isolation & purification
Sucrose* / metabolism

Substances

Sucrose
DNA Transposable Elements