Treatment of Acute Ischemic Stroke: The Last 30 Years of Trials and Tribulations

Cardiol Rev. 2024 May-Jun;32(3):203-216. doi: 10.1097/CRD.0000000000000663. Epub 2024 Mar 23.

Abstract

The landscape of acute ischemic stroke management has undergone a substantial transformation over the past 3 decades, mirroring our enhanced comprehension of the pathology and progress in diagnostic techniques, therapeutic interventions, and preventive measures. The 1990s marked a pivotal moment in stroke care with the integration of intravenous thrombolytics. However, the most significant paradigm shift in recent years has undoubtedly been the advent of endovascular thrombectomy. This article endeavors to deliver an exhaustive analysis of this revolutionary progression.

MeSH terms

  • Brain Ischemia* / drug therapy
  • Endovascular Procedures* / methods
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Ischemic Stroke* / therapy
  • Stroke* / drug therapy
  • Stroke* / therapy
  • Treatment Outcome

Substances

  • Fibrinolytic Agents