Lesion of slit-like stenosis underestimated by fractional flow reserve based on computed tomography images

Tetsuya Matsuyama; Tatsuhiro Fujimura; Takayuki Okamura

doi:10.1007/s10554-024-03077-z

Lesion of slit-like stenosis underestimated by fractional flow reserve based on computed tomography images

Int J Cardiovasc Imaging. 2024 Mar 23. doi: 10.1007/s10554-024-03077-z. Online ahead of print.

Authors

Tetsuya Matsuyama¹, Tatsuhiro Fujimura¹, Takayuki Okamura²

Affiliations

¹ Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-kogushi, Ube, Yamaguchi, 755-8505, Japan.
² Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-kogushi, Ube, Yamaguchi, 755-8505, Japan. t-okamu@yamaguchi-u.ac.jp.

PMID: 38519823
DOI: 10.1007/s10554-024-03077-z

Abstract

This case report discusses a 74-year-old man presenting with angina pectoris. Coronary computed tomography angiography suggested only mild stenosis in the mid left anterior descending artery (LAD), with fractional flow reserve based on computed tomography images (FFRct) value of 0.87. However, coronary angiography revealed slit-like stenosis in the mid LAD, and the invasive fractional flow reserve (FFR) was measured at 0.72, demonstrating a deviation from the FFRct value.

Keywords: Coronary artery disease; Coronary computed tomography angiography; Fractional flow reserve; Optical coherence tomography.