CD-Net: Cascaded 3D Dilated convolutional neural network for pneumonia lesion segmentation

Comput Biol Med. 2024 May:173:108311. doi: 10.1016/j.compbiomed.2024.108311. Epub 2024 Mar 16.

Abstract

COVID-19 is a global pandemic that has caused significant global, social, and economic disruption. To effectively assist in screening and monitoring diagnosed cases, it is crucial to accurately segment lesions from Computer Tomography (CT) scans. Due to the lack of labeled data and the presence of redundant parameters in 3D CT, there are still significant challenges in diagnosing COVID-19 in related fields. To address the problem, we have developed a new model called the Cascaded 3D Dilated convolutional neural network (CD-Net) for directly processing CT volume data. To reduce memory consumption when cutting volume data into small patches, we initially design a cascade architecture in CD-Net to preserve global information. Then, we construct a Multi-scale Parallel Dilated Convolution (MPDC) block to aggregate features of different sizes and simultaneously reduce the parameters. Moreover, to alleviate the shortage of labeled data, we employ classical transfer learning, which requires only a small amount of data while achieving better performance. Experimental results conducted on the different public-available datasets verify that the proposed CD-Net has reduced the negative-positive ratio and outperformed other existing segmentation methods while requiring less data.

Keywords: Convolutional neural network; Lesion segmentation; Transfer learning.

Publication types

  • Review

MeSH terms

  • COVID-19* / diagnostic imaging
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Neural Networks, Computer
  • Pneumonia*
  • Tomography, X-Ray Computed