Analysis of Nanoparticles' Effects on Drug-Induced Psoriasis

Methods Mol Biol. 2024:2789:129-135. doi: 10.1007/978-1-0716-3786-9_13.

Abstract

Psoriasis, an auto-inflammatory disorder, has major manifestations in the skin but can affect other organs. Currently, this condition has no cure, and the treatments include anti-inflammatory medications. Nanoparticles are widely used for drug delivery and have found successful applications in therapy for cancer and infectious diseases. Nanoparticles can also be used to deliver anti-inflammatory drugs to sites of inflammation. Moreover, some nanotechnology platforms possess intrinsic anti-inflammatory properties and may benefit the therapy of inflammation-driven disorders. Herein, we present a protocol to study nanotechnology concepts' anti-inflammatory properties in a chemically-induced psoriasis model.

Keywords: Auto-inflammatory reactions; Cytokines; Hypersensitivity; Inflammation; Nanoparticles; Psoriasis; Skin.

MeSH terms

  • Anti-Inflammatory Agents / pharmacology
  • Humans
  • Inflammation / drug therapy
  • Nanoparticles*
  • Psoriasis* / chemically induced
  • Psoriasis* / drug therapy
  • Skin

Substances

  • Anti-Inflammatory Agents