Crosstalk between TGF-β and EGF receptors via direct phosphorylation

Aristidis Moustakas

doi:10.1083/jcb.202403075

Crosstalk between TGF-β and EGF receptors via direct phosphorylation

J Cell Biol. 2024 Apr 1;223(4):e202403075. doi: 10.1083/jcb.202403075. Epub 2024 Mar 20.

Author

Aristidis Moustakas¹

Affiliation

¹ Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

PMID: 38506732
PMCID: PMC10955040 (available on 2024-09-20)
DOI: 10.1083/jcb.202403075

Abstract

Aristidis Moustakas discusses work from Ye-Guang Chen and colleagues (https://doi.org/10.1083/jcb.202307138) on a new mechanism by which TGF-β modulates HER2 signaling in mammary epithelia.

MeSH terms

Animals
ErbB Receptors* / genetics
Phosphorylation
Transforming Growth Factor beta*

Substances

ErbB Receptors
Transforming Growth Factor beta

Abstract

MeSH terms

Substances

Grants and funding