Analysis and comparative study of a deterministic mathematical model of SARS-COV-2 with fractal-fractional operators: a case study

Sci Rep. 2024 Mar 18;14(1):6431. doi: 10.1038/s41598-024-56557-6.

Abstract

In this paper, we investigate a fractal-fractional-order mathematical model with the influence of hospitalized patients and the impact of vaccination with fractal-fractional operators. The respective derivatives are considered in the Caputo, Caputo Fabrizio, and Atangana-Baleanu senses of fractional order α and fractal dimension τ . For the proposed problem, some results regarding basic reproduction number and stability are given. Using the next-generation matrix approach, we have investigated the global and local stability of several types of equilibrium points. We provide a detailed analysis of the existence and uniqueness of the solution. Moreover, we fit the model with the real data of Pakistan from June 01, 2020, till March 24, 2021. Then, we use the fractal-fractional derivative to find a numerical solution for the model. MATLAB software is used for numerical illustration. Graphical presentations corresponding to different parameteric values are given as well.

Keywords: Comparison; Data fitting; Epidemic model; Fractal-fractional model; Parameters estimation; SARS-CoV-2.

MeSH terms

  • Basic Reproduction Number
  • COVID-19*
  • Fractals*
  • Humans
  • Pakistan
  • SARS-CoV-2