1 Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany. lutz.hein@pharmakol.uni-freiburg.de.
2 Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
3 Institute of Pharmacology, Hannover Medical School, Hannover, Germany.