[A Case of Pathologically Complete Response after Preoperative Chemotherapy in a Locally Advanced Rectal Cancer]

Gan To Kagaku Ryoho. 2024 Mar;51(3):332-333.
[Article in Japanese]

Abstract

The case is a 78-year-old male. The chief complaint was melena and weight loss. After careful examination, the patient was diagnosed with advanced rectal cancer, and 3 courses of capecitabine plus oxaliplatin therapy were performed as preoperative chemotherapy. He underwent robot-assisted laparoscopic rectal resection, D3 lymphadenectomy, lateral lymphadenectomy, and temporary colostomy, and was discharged on hospital day 15. Postoperative pathological diagnosis showed only ulcerative lesions in the rectum, and malignant cells could not be confirmed. After postoperative adjuvant chemotherapy, the patient is alive without recurrence on an outpatient basis. There are many reports that it is slightly lower than radiotherapy. Therefore, it is important to select a more appropriate preoperative treatment, and the concentration of future cases is recognized.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Chemotherapy, Adjuvant
  • Humans
  • Male
  • Oxaliplatin / therapeutic use
  • Pathologic Complete Response
  • Proctectomy*
  • Rectal Neoplasms* / drug therapy
  • Rectal Neoplasms* / pathology
  • Rectal Neoplasms* / surgery
  • Rectum / pathology

Substances

  • Oxaliplatin