Objective: To analyze survival data of cancer from 1970 to 2014 in Zhongshan City, Guangdong Province, and provide scientific basis for cancer prevention and control in Zhongshan City. Methods: The tumor incidence data of Zhongshan City, Guangdong Province from 1970 to 2014 were collected from Zhongshan Cancer Registry, and all patients were followed up to December 31, 2019. The standardized 5-year net survival rates and their annual percentage change (APC) and average annual percentage change (AAPC) for total and major cancers at different times were used to describe statistical analysis. The standardized survival rates were weighted using the International Cancer Survival Standard Age Coefficients. Results: There were 78 854 cancer patients eligible for the study in Zhongshan City of Guangdong Province from 1970 to 2014, among which lung cancer (13 466 cases, 17.08%), nasopharyngeal cancer (9715 cases, 12.32%) and liver cancer (9707 cases, 12.31%) were the main types of cancer. The morphology verification was 69.87% in the whole of cancers and the ranges were 21.07% to 97.00% in major cancers. From 2010 to 2014, the 5-year age-standardized net survival rates of cancers for all, males and females in Zhongshan City were 39.74%, 30.92% and 52.47%, in which were 97.98% for thyroid cancer, 74.29% for brain and central nervous system tumors, 73.92% for nasopharyngeal cancer, 50.23% for colorectal cancer, 81.38% for female breast cancer, 78.81% for uterine body cancer, 68.57% for cervical cancer, 49.33% for prostate cancer, 16.19% for lung cancer , 12.14% for liver cancer, and 11.78% for esophageal cancer, respectively. The survival rates of all cancers in Zhongshan City showed an increasing trends in 1970-2014 (AAPC=1.5%, P=0.025), and it was higher in female cancers than that of male in all periods. Conclusion: The standardized 5-year net survival rates of all and major cancers in Zhongshan City of Guangdong Province show an increasing trend from 1970 to 2014, but they are still at a medium-low levels compared with the countries and regions participating in CONCORD-3 project, suggesting that Zhongshan should continue to strengthen cancer prevention and control.
目的： 分析广东省中山市1970—2014年恶性肿瘤生存资料，为中山市肿瘤防控提供科学依据。 方法： 广东省中山市1970—2014年恶性肿瘤发病资料来源于中山市肿瘤登记处，随访截至2019年12月31日。统计指标包括总体和主要恶性肿瘤不同时期的标化5年净生存率及其年度变化百分比（APC）和平均年度变化百分比（AAPC）。标化生存率采用国际癌症生存标准年龄结构进行加权。 结果： 广东省中山市1970—2014年符合研究条件的恶性肿瘤新发病例共78 854例，其中肺癌（13 466例，17.08%）、鼻咽癌（9 715例，12.32%）和肝癌（9 707例，12.31%）较多，总体病理学诊断比例（MV%）为69.87%，主要恶性肿瘤MV%在21.07%～97.00%之间。2010—2014年，中山市恶性肿瘤总体、男性、女性的标化5年净生存率分别为39.74%、30.92%和52.47%，主要恶性肿瘤标化5年净生存率分别为甲状腺癌97.98%，脑及中枢神经系统肿瘤74.29%，鼻咽癌73.92%，结直肠癌50.23%，女性乳腺癌81.38%，子宫体癌78.81%，宫颈癌68.57%，前列腺癌49.33%，肺癌16.19%，肝癌12.14%，食管癌11.78%。1970—2014年，中山市总体恶性肿瘤标化5年净生存率呈上升趋势（AAPC=1.5%，P=0.025），不同时期女性恶性肿瘤标化5年净生存率均高于男性。 结论： 1970—2014年广东省中山市总体及主要恶性肿瘤的标化5年净生存率呈上升趋势，但与全球CONCORD-3项目参与国家和地区相比，近期净生存率仍处于中低水平，提示中山市应继续加强肿瘤防控。.