Phase-driven progress in nanophotonic biosensing

Light Sci Appl. 2024 Mar 18;13(1):76. doi: 10.1038/s41377-024-01415-3.

Abstract

In the continuous pursuit of enhancing the sensitivity of nanophotonic biosensors by leveraging phase phenomena, a recent development involved the engineering of an atomically thin Ge2Sb2Te5 layer on a silver nanofilm to generate large Goos-Hänchen-shifts associated with phase singularities. The resulting detection limit reached ~7 × 10-7 RIU.