Follow-up of cognitive impairment and inflammatory profile in individuals with mild COVID-19

Abstract

Individuals who experience mild COVID-19 can suffer from long-lasting cognitive symptoms. Notably, 26% of these individuals experience difficulties with visuospatial abilities six months after infection. However, among those who initially exhibited visuoconstructive impairments, 66% showed improvement or complete reversal over time. Additionally, changes in cytokine levels, particularly CCL11, HGF, and CXCL10, were observed. These results suggest a potential link between ongoing cognitive issues and elevated levels of pro-inflammatory cytokines, which merits further investigation.

Keywords: Post-acute COVID-19 syndrome. Neuroinflammation. Cytokine. Cognitive symptoms. Visuospatial processing.