Analysis, treatment modality and demographic characteristics of urolithiasis patients visiting Korle-Bu Teaching Hospital in Ghana

Evans Ametefe Akpakli; Emmanuel Asante; Matthew Yamoah Kyei; Kenneth Klufio; Bernard Toboh; James Edward Mensah

doi:10.4103/jwas.jwas_86_23

Analysis, treatment modality and demographic characteristics of urolithiasis patients visiting Korle-Bu Teaching Hospital in Ghana

J West Afr Coll Surg. 2024 Jan-Mar;14(1):94-101. doi: 10.4103/jwas.jwas_86_23. Epub 2023 Dec 14.

Authors

Evans Ametefe Akpakli¹, Emmanuel Asante², Matthew Yamoah Kyei³, Kenneth Klufio¹, Bernard Toboh¹, James Edward Mensah³

Affiliations

¹ Department of Surgery, Korle-Bu Teaching Hospital, Accra, Ghana.
² Department of Surgery, University of Ghana Medical Centre, Accra, Ghana.
³ School of Medicine and Dentistry, College of Health Sciences, Accra, Ghana.

Abstract

Background: Globally urolithiasis is on the rise and gradually becoming a public health concern due to the associated complications. This study reviewed the demographic characteristics, the chemical composition of stones, treatment modality and duration of hospitalisation of urolithiasis patients at Korle-Bu Teaching Hospital, Accra, Ghana.

Materials and methods: This was a retrospective study conducted between March 2019 and April 2022. Data from consecutive patients treated for urolithiasis were used for this study. Data on demographic characteristics, stones chemical composition, urine factors, urolithiasis treatment modality and duration of hospital stay after therapy were collated and analysed using descriptive and inferential approaches.

Results: The age of the patients ranged from 2 to 75 years with a mean of 45 (±13.4). The predominant age group for stone formation was 30-39 years - 52(26.3%). Urolithiasis was common among patients in the formal employment sector: 81(40.9%). All stones had two or more chemical compositions, with the combination of calcium oxalate monohydrate, calcium oxalate dihydrate and uric acid being the predominant stone type: 88(57.5%). Ureteroscopy with semi-rigid and Percutaneous nephrolithotomy were the predominant treatment modalities: 105(53.0%) and 74(37.4%), respectively. Escherichia coli was responsible for most urinary tract infections in urolithiasis patients 8(4.0%) and the least duration of hospital stay after the procedure was associated with the use of semi-rigid ureteroscope as the treatment modality with a median duration of 2 days (1-2 days) with P < 0.0001.

Conclusions: Urolithiasis was predominant among professionals in the formal sector. All stones were mixed with Calcium oxalate monohydrate, calcium oxalate dihydrate, and uric acid combination being the majority. Ureteroscopy with semi-rigid and percutaneous nephrolithotomy were the common treatment modality.

Keywords: Chemical composition; treatment modality; urolithiasis.