Advances in self-assembled nanotechnology in tumor therapy

Colloids Surf B Biointerfaces. 2024 May:237:113838. doi: 10.1016/j.colsurfb.2024.113838. Epub 2024 Mar 11.

Abstract

The emergence of nanotechnology has opened up a new way for tumor therapy. Among them, self-assembled nanotechnology has received extensive attention in medicine due to its simple preparation process, high drug-loading capacity, low toxicity, and low cost. This review mainly summarizes the preparation methods of self-assembled nano-delivery systems, as well as the self-assembled mechanism of carrier-free nanomedicine, polymer-carried nanomedicine, polypeptide, and metal drugs, and their applications in tumor therapy. In addition, we discuss the advantages and disadvantages, future challenges, and opportunities of these self-assembled nanomedicines, which provide important references for the development and application of self-assembled nanotechnology in the field of medical therapy.

Keywords: Delivery system; Nanotechnology; Self-assembly; Tumor therapy.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems*
  • Humans
  • Nanomedicine
  • Nanotechnology
  • Neoplasms* / drug therapy
  • Peptides / therapeutic use

Substances

  • Peptides