A prospects tool in virus research: Analyzing the applications of organoids in virus studies

Acta Trop. 2024 Jun:254:107182. doi: 10.1016/j.actatropica.2024.107182. Epub 2024 Mar 11.

Abstract

Organoids have emerged as a powerful tool for understanding the biology of the respiratory, digestive, nervous as well as urinary system, investigating infections, and developing new therapies. This article reviews recent progress in the development of organoid and advancements in virus research. The potential applications of these models in studying virul infections, pathogenesis, and antiviral drug discovery are discussed.

Keywords: Application; Organoid; Virus.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use
  • Drug Discovery / methods
  • Humans
  • Organoids* / virology
  • Virus Diseases* / drug therapy
  • Virus Diseases* / virology
  • Viruses / classification
  • Viruses / drug effects
  • Viruses / growth & development
  • Viruses / pathogenicity

Substances

  • Antiviral Agents