An effective colorectal polyp classification for histopathological images based on supervised contrastive learning

Comput Biol Med. 2024 Apr:172:108267. doi: 10.1016/j.compbiomed.2024.108267. Epub 2024 Mar 8.

Abstract

Early detection of colon adenomatous polyps is pivotal in reducing colon cancer risk. In this context, accurately distinguishing between adenomatous polyp subtypes, especially tubular and tubulovillous, from hyperplastic variants is crucial. This study introduces a cutting-edge computer-aided diagnosis system optimized for this task. Our system employs advanced Supervised Contrastive learning to ensure precise classification of colon histopathology images. Significantly, we have integrated the Big Transfer model, which has gained prominence for its exemplary adaptability to visual tasks in medical imaging. Our novel approach discerns between in-class and out-of-class images, thereby elevating its discriminatory power for polyp subtypes. We validated our system using two datasets: a specially curated one and the publicly accessible UniToPatho dataset. The results reveal that our model markedly surpasses traditional deep convolutional neural networks, registering classification accuracies of 87.1% and 70.3% for the custom and UniToPatho datasets, respectively. Such results emphasize the transformative potential of our model in polyp classification endeavors.

Keywords: Big transfer; Colonic polyp classification; Computer-aided diagnosis; Histopathology image classification; Supervised contrastive learning; Transfer learning.

MeSH terms

  • Adenomatous Polyps*
  • Colonic Polyps* / diagnostic imaging
  • Diagnosis, Computer-Assisted / methods
  • Diagnostic Imaging
  • Humans
  • Neural Networks, Computer