Physical condition and perceived fatigue in post-covid patients: An observational descriptive study

Sao Paulo Med J. 2024 Mar 8;142(4):e2023167. doi: 10.1590/1516-3180.2023.0167.R1.04122023. eCollection 2024.

Abstract

Background: Patients with severe coronavirus disease 2019 (COVID-19) often require hospital admission and experience sequelae such as chronic fatigue or low muscle mass.

Objective: To analyze the functional capacity of a cohort of patients with severe acute respiratory syndrome coronavirus 2 who required hospitalization.

Design and setting: An observational descriptive study was conducted on post-COVID-19 patients referred to the Rehabilitation Department of Gregorio Marañón Hospital (Madrid, SPAIN).

Methods: Cardiorespiratory fitness, muscle strength, body composition, and perception of fatigue and dyspnea were analyzed. Furthermore, the existing correlations between clinical variables and physical conditions were analyzed.

Results: Forty-two patients who required hospital admission (80 ± 22.45 days) or intensive care unit (ICU) admission (58 ± 10.52 days) were analyzed. They presented with decreased strength, respiratory capacity, and moderate-to-severe perceived fatigue. Additionally, an inverse correlation was found between right-handgrip strength and days in the ICU, as well as the 6-minute walk test for women. Similarly, strength and fitness were negatively associated with perceived fatigue.

Conclusions: Post-COVID-19 patients showed low muscle function and low levels of physical fitness associated with high perceived fatigue.

Publication types

  • Observational Study

MeSH terms

  • Body Composition
  • COVID-19*
  • Cardiorespiratory Fitness*
  • Disease Progression
  • Female
  • Hand Strength
  • Humans
  • Male