Detection of doxycycline by using a tapered droplet structure fiber sensor

Zhitao Yang; Shan Wang; Shijie Wang; Sijia Han; Lingzui Wei; Wenlong Yang

doi:10.1063/5.0164105

Detection of doxycycline by using a tapered droplet structure fiber sensor

Rev Sci Instrum. 2024 Mar 1;95(3):035004. doi: 10.1063/5.0164105.

Authors

Zhitao Yang¹, Shan Wang¹, Shijie Wang¹, Sijia Han¹, Lingzui Wei¹, Wenlong Yang²

Affiliations

¹ School of Sciences, Harbin University of Science and Technology, Harbin 150080, China.
² School of Measurement and Communication Engineering, Harbin University of Science and Technology, Harbin 150080, China.

PMID: 38477656
DOI: 10.1063/5.0164105

Abstract

The abuse of doxycycline (DC) can lead to residues in animals and water environments, which severely threaten human health; however, currently accepted detection methods are generally complicated and cannot be used for real-time detection. Therefore, developing a method for rapid real-time detection of DC microcontent residues is highly important. Herein, based on the Mach-Zehnder interference, we propose a simple tapered droplet structure fiber sensor with a high detection sensitivity. By modifying the sensing region with a molecularly imprinted polymer film of DC, this sensor realizes the specific detection of DC and has a detection sensitivity of 58.81 pm/ppm for DC in a large concentration range of 0-300 ppm. This sensor can be used to detect DC microcontent in aqueous solutions in real time.