How Does Radiation Affect Curcumin Raw Material?

Int J Mol Sci. 2024 Feb 21;25(5):2524. doi: 10.3390/ijms25052524.

Abstract

Turmeric, known for its curcuminoid-rich rhizome, particularly curcumin, exhibits notable antioxidant and antiviral properties. The likelihood of microbial contamination necessitates finding reliable techniques for subjecting the sample to radiation from this plant-based raw material. One alternative is to expose curcumin to radiation (e-beam), which was carried out as part of this research. Confirmation of the lack of curcumin decomposition was carried out using HPLC-DAD/MS techniques. Additionally, using the EPR technique, the generated free radicals were defined as radiation effects. Using a number of methods to assess the ability to scavenge free radicals (DPPH, ABTS, CUPRAC, and FRAP), a slight decrease in the activity of curcumin raw material was determined. The analysis of the characteristic bands in the FT-IR spectra allowed us to indicate changes in the phenolic OH groups as an effect of the presence of radicals formed.

Keywords: antioxidant; curcumin; electron beam irradiation.

MeSH terms

  • Antioxidants
  • Curcumin*
  • Diarylheptanoids
  • Free Radicals
  • Spectroscopy, Fourier Transform Infrared

Substances

  • Curcumin
  • Diarylheptanoids
  • Antioxidants
  • Free Radicals

Grants and funding

This research was funded by Exchange programme for scientists as part of bilateral cooperation from the Polish National Agency for Academic Exchange grant number BPN/BIL/2021/1/00020.