Uses and limitations of small-volume biopsies for the diagnosis of lymphoma

Megan J Fitzpatrick; Aliyah R Sohani; Amy Ly

doi:10.1111/cyt.13372

Uses and limitations of small-volume biopsies for the diagnosis of lymphoma

Cytopathology. 2024 Mar 10. doi: 10.1111/cyt.13372. Online ahead of print.

Authors

Megan J Fitzpatrick¹, Aliyah R Sohani¹, Amy Ly¹

Affiliation

¹ Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

PMID: 38462899
DOI: 10.1111/cyt.13372

Abstract

Although surgical biopsy remains the gold standard for the diagnosis of lymphoma, small-volume biopsies including fine-needle aspiration and core needle biopsy are increasingly being used as a first line diagnostic tool. Small-volume biopsies are safe, rapid and cost effective; however, diagnostic utility varies by lymphoma subtype. It is important for pathologists and clinicians to recognize both the strengths and limitations of such biopsies.

Keywords: core needle biopsy; fine-needle aspiration; lymphoma; small-volume biopsy; surgical biopsy.

Publication types

Review