Intratumoral NK cell delivery combined with neutralization of the NKG2A pathway as treatment for solid cancer

Ignacio Melero; Carmen Molina; Cristina Eguizabal; Maite Alvarez

doi:10.1038/s41435-024-00267-6

Intratumoral NK cell delivery combined with neutralization of the NKG2A pathway as treatment for solid cancer

Genes Immun. 2024 Mar 9. doi: 10.1038/s41435-024-00267-6. Online ahead of print.

Authors

Ignacio Melero^{1

2

3

4

5}, Carmen Molina^{6

7}, Cristina Eguizabal^{8

9

10}, Maite Alvarez^{11

12

13

14

15}

Affiliations

¹ Program for Immunology and Immunotherapy, CIMA. Universidad de Navarra, Pamplona, Spain. imelero@unav.es.
² Navarra Institute for Health Research (IdiSNA), Pamplona, Spain. imelero@unav.es.
³ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. imelero@unav.es.
⁴ Departments of Immunology and Oncology, Clínica Universidad de Navarra, Pamplona, Spain. imelero@unav.es.
⁵ Red de Inmunoterapia del Cáncer (REINCA), Madrid, Spain. imelero@unav.es.
⁶ Program for Immunology and Immunotherapy, CIMA. Universidad de Navarra, Pamplona, Spain.
⁷ Navarra Institute for Health Research (IdiSNA), Pamplona, Spain.
⁸ Red de Inmunoterapia del Cáncer (REINCA), Madrid, Spain.
⁹ Cell Therapy, Stem Cells and Tissue Group, Biobizkaia Health Research Institute, Barakaldo, Spain.
¹⁰ Advanced Therapies Unit, Basque Center for Blood Transfusion and Human Tissues, Osakidetza, Galdakao, Spain.
¹¹ Program for Immunology and Immunotherapy, CIMA. Universidad de Navarra, Pamplona, Spain. maite.alvarezrodriguez@bio-bizkaia.eus.
¹² Navarra Institute for Health Research (IdiSNA), Pamplona, Spain. maite.alvarezrodriguez@bio-bizkaia.eus.
¹³ Red de Inmunoterapia del Cáncer (REINCA), Madrid, Spain. maite.alvarezrodriguez@bio-bizkaia.eus.
¹⁴ Cell Therapy, Stem Cells and Tissue Group, Biobizkaia Health Research Institute, Barakaldo, Spain. maite.alvarezrodriguez@bio-bizkaia.eus.
¹⁵ Advanced Therapies Unit, Basque Center for Blood Transfusion and Human Tissues, Osakidetza, Galdakao, Spain. maite.alvarezrodriguez@bio-bizkaia.eus.

PMID: 38461213
DOI: 10.1038/s41435-024-00267-6

No abstract available

Grants and funding