Background: Lung cancer is the malignant tumor with the highest incidence rate and the heaviest disease burden in China. In recent years, lung cancer has shown a high incidence trend, seriously affecting the health of the population. In this paper, we analyze the characteristics of lung cancer incidence in 2019 and the trend of incidence rate from 2010-2019 in the tumor registration area of Gansu province, in order to provide a reference basis for the development of lung cancer prevention and control strategies in Gansu province.
Methods: By analyzing the cases of lung cancer incidence in the tumor registration area of Gansu province in 2019, we calculated the incidence rate, medium incidence rate, world incidence rate and other related indexes; we used Joinpoint to calculate the annual percentage change (APC) for trend analysis.
Results: In 2019, a total of 3757 new cases of lung cancer were reported in Gansu province, accounting for 14.96% of all new malignant tumors. The incidence rate, medium incidence rate and world incidence rate and world rate of lung cancer were 40.52/10⁵, 25.78/10⁵, 25.86/10⁵; and the cumulative rate of 0-74 years old, and the truncation rate of 35-64 years old were 3.23%, 40.03/10⁵, respectively. The incidence of lung cancer rises with age, and is high in the age group of 40 years and above, and the incidence peaks in the male and female populations in the group of 75 years and above, and the group of 80 years and above, respectively. The crude incidence rate of lung cancer in the tumor registration area of Gansu province from 2010-2019 showed an overall increasing trend, and the rate of increase was relatively fast, with an APC 5.39% (P<0.05); Separately, according to gender, urban and rural areas, the incidence of lung cancer in all populations showed an increasing trend, and the APC of male, female, urban and rural populations were 4.98%, 6.39%, 6.26%, and 4.64%, respectively (all P<0.05). According to the trend analysis of lung cancer incidence rate by age group, only lung cancer incidence in the age group of 65 years and above increased at an annual average rate of 4.15% (P<0.05).
Conclusions: The incidence rate of lung cancer in the tumor registration area of Gansu province from 2010 to 2019 shows a rising trend year by year, and there are differences in the incidence of lung cancer in people of different genders, regions and age groups, so comprehensive prevention and control work should be carried out for the key populations of lung cancer incidence.
【中文题目：2010-2019年甘肃省肿瘤登记地区肺癌发病的流行病学特征分析】 【中文摘要：背景与目的 肺癌是中国发病率最高、疾病负担最重的恶性肿瘤。近年来，肺癌呈高发趋势，严重影响人群健康。本文通过分析甘肃省肿瘤登记地区2019年肺癌发病特征及2010-2019年发病率趋势，为甘肃省肺癌防控策略制定提供参考依据。方法 通过分析甘肃省肿瘤登记地区2019年肺癌发病个案，计算发病率、中标发病率、世标发病率等相关指标；采用Joinpoint计算年度变化百分比（annual percent change, APC），进行趋势分析。结果 2019年甘肃省共报告肺癌新发病例3757例，占所有新发恶性肿瘤的14.96%，肺癌发病率、中标率、世标率分别为40.52/10万、30.91/10万和25.86/10万，0-74岁累积率、35-64岁截缩率分别为3.23%和40.03/10万。肺癌发病随着年龄增长而上升，在≥40岁组高发，男、女性人群分别在≥75岁组、≥80岁组达到发病高峰。2010-2019年甘肃省肿瘤登记地区肺癌粗发病率总体呈上升趋势，且上升速度较快，APC为5.39%（P<0.05）；分别按照性别、城乡进行统计，各人群肺癌发病率均呈上升趋势，男性、女性、城市、农村人群APC分别为4.98%、6.39%、6.26%和4.64%（P均<0.05）。按照年龄组肺癌发病率进行趋势分析，仅≥65岁组人群肺癌发病以年均4.15%的速度上升（P<0.05）。结论 2010-2019年甘肃省肿瘤登记地区肺癌发病率呈现逐年上升趋势，不同性别、地区及年龄组人群肺癌发病存在差异，应针对肺癌发病重点人群开展综合防控工作。 】 【中文关键词：肺肿瘤；发病特征；变化趋势】.
Keywords: Change trend; Incidence characteristics; Lung neoplasms.