Descending necrotising mediastinitis: a rare entity in children

BMJ Case Rep. 2024 Mar 7;17(3):e258304. doi: 10.1136/bcr-2023-258304.

Abstract

We present a case of descending necrotising mediastinitis (DNM) originating from a retropharyngeal abscess in a healthy early childhood patient. The patient had a history of fever, odynophagia and refusal to eat, followed by rapid deterioration of the clinical state. Cervicothoracic CT was performed, which revealed a right parapharyngeal abscess, extending to the mediastinum and occupying the retropharyngeal/visceral space, with gaseous content throughout this collection, associated with bilateral pleural effusion, aspects compatible with DNM. She started broad-spectrum antibiotic therapy and transoral drainage of the parapharyngeal and retropharyngeal collections was performed under general anaesthesia. She was admitted to the intensive care unit. The patient showed clinical, analytical and imaging improvement, having been transferred to the ear, nose and throat department, with favourable evolution. Early diagnosis of DNM by cervicothoracic CT and multidisciplinary approaches, including intensive care, broad-spectrum antibiotics and surgical intervention, are crucial to minimise the morbidity and mortality.

Keywords: Ear, nose and throat/otolaryngology; Head and neck surgery; Otolaryngology / ENT; Paediatric intensive care; Paediatrics.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Drainage / methods
  • Female
  • Humans
  • Mediastinitis* / diagnostic imaging
  • Mediastinitis* / therapy
  • Mediastinum / diagnostic imaging
  • Neck
  • Necrosis / complications
  • Retropharyngeal Abscess* / diagnostic imaging
  • Retropharyngeal Abscess* / therapy