Extraction, structure and antioxidant activity of the polysaccharides from morels (Morchella spp.): A review

Int J Biol Macromol. 2024 Apr;264(Pt 2):130656. doi: 10.1016/j.ijbiomac.2024.130656. Epub 2024 Mar 5.

Abstract

Morels (Morchella spp.), which are cultivated only in a few regions of the world, are edible mushrooms known for their various properties including antioxidation, immune regulation, antiinflammation, and antitumor effects. Polysaccharides from Morchella are principally responsible for its antioxidant activity. This paper reviews the extraction, purification, structural analysis and antioxidant activity of Morchella polysaccharides (MPs), providing updated research progress. Meanwhile, the structural-property relationships of MPs were further discussed. In addition, based on in vitro and in vivo studies, the major factors responsible for the antioxidant activity of MPs were summarized including scavenging free radicals, reduction capacity, inhibitory lipid peroxidation activity, regulating the signal transduction pathway, reducing the production of ROS and NO, etc. Finally, we hope that our research can provide a reference for further research and development of MPs.

Keywords: Antioxidant activity; Morchella spp.; Polysaccharide; Structure.

Publication types

  • Review

MeSH terms

  • Agaricales* / chemistry
  • Antioxidants / metabolism
  • Ascomycota* / chemistry
  • Polysaccharides / analysis
  • Polysaccharides / pharmacology

Substances

  • Antioxidants
  • Polysaccharides