Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinosinusitis with nasal polyps, asthma and the development of significant airway symptoms following the ingestion of aspirin and other nonsteroid anti-inflammatory drugs (NSAIDs). At present, aspirin challenge is the gold standard for diagnosis. Aspirin desensitization and aspirin therapy after desensitization (ATAD) is one of the classical therapies. This paper described the application of aspirin desensitization and ATAD in AERD and provided the reference for the comprehensive treatment of AERD.
阿司匹林加重呼吸系统疾病（AERD）是以慢性鼻窦炎伴鼻息肉、哮喘、摄入阿司匹林或其他非甾体类抗炎药（NSAID）后呼吸道症状发作为特点的临床综合征。目前阿司匹林激发试验是其诊断金标准，而阿司匹林脱敏及阿司匹林脱敏后维持治疗（ATAD）是经典的治疗方法之一。本文阐述了阿司匹林脱敏及ATAD在AERD中的应用，为AERD患者的综合治疗提供参考。.