[Pulmonary artery stenting in chronic thromboembolic pulmonary hypertension: a report of 2 cases]

Zhonghua Jie He He Hu Xi Za Zhi. 2024 Mar 12;47(3):228-232. doi: 10.3760/cma.j.cn112147-20230921-00184.
[Article in Chinese]

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a pulmonary vascular disease characterized by an insidious onset, progressive deterioration, and poor prognosis. It is distinguished by the thrombotic organization within the pulmonary arteries, leading to vascular stenosis or occlusion. This results in a progressive increase in pulmonary vascular resistance and pulmonary arterial pressure, ultimately leading to right heart failure. In recent years, balloon pulmonary angioplasty (BPA) has emerged as an effective treatment option for patients ineligible for pulmonary endarterectomy (PEA). However, the use of stents in patients with suboptimal balloon dilation remains controversial. This article describes two cases of chronic thromboembolic pulmonary hypertension (CTEPH) in which balloon angioplasty yielded unsatisfactory results, subsequently leading to stent placement. Following stent implantation, there was improved blood flow, significant reduction in pulmonary arterial pressure, and notable alleviation of patient symptoms. One-year follow-up showed no recurrence of stenosis within the stent, suggesting potential guidance for the use of pulmonary artery stenting as a treatment modality for CTEPH. This report provided new insights into the therapeutic approach for CTEPH.

慢性血栓栓塞性肺动脉高压(chronic thromboembolic pulmonary hypertension,CTEPH)是一种发病隐匿、进行性加重且预后较差的肺血管疾病,以肺动脉血栓机化致血管狭窄或闭塞,肺血管阻力和肺动脉压力进行性升高,最终导致右心功能衰竭为特征。近年来,经皮肺动脉球囊成形术(balloon pulmonary angioplasty,BPA)为不能行肺动脉内膜剥脱术(pulmonary endarterectomy,PEA)的患者提供了有效治疗方法,但是对于球囊扩张不理想的患者能否进行支架植入尚没有明确定论。本文介绍了两例CTEPH病变血管经过球囊扩张后效果不理想,最终植入支架,支架植入后血流通畅、肺动脉压力明显下降、患者症状明显改善,随访1年后支架内未见再狭窄的病例,以期为肺动脉支架植入治疗CTEPH提供推荐意见和指导价值。本报道为CTEPH疾病的治疗方式提供了新的思考。.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Angioplasty, Balloon*
  • Constriction, Pathologic
  • Endarterectomy
  • Humans
  • Hypertension, Pulmonary* / etiology
  • Hypertension, Pulmonary* / surgery
  • Pulmonary Artery / surgery