Diffuse Kaposi sarcoma with oral involvement in a person diagnosed with human immunodeficiency virus/acquired immune deficiency syndrome: A case report

Latifa Berrezouga; Nada Alouani; Ikbel Kooli; Ahlem Bellalah; Mohamed Chakroun

doi:10.1177/2050313X241235815

Diffuse Kaposi sarcoma with oral involvement in a person diagnosed with human immunodeficiency virus/acquired immune deficiency syndrome: A case report

SAGE Open Med Case Rep. 2024 Mar 4:12:2050313X241235815. doi: 10.1177/2050313X241235815. eCollection 2024.

Authors

Latifa Berrezouga^{1

2

3}, Nada Alouani^{1

2

3}, Ikbel Kooli⁴, Ahlem Bellalah⁵, Mohamed Chakroun⁴

Affiliations

¹ Department of Microbiology and Immunology, Faculty of Dental Medicine, University of Monastir, Monastir, Tunisia.
² Department of Endodontics, Dental Clinic, University of Monastir, Tunisia.
³ Laboratory of Medical and Molecular Parasitology and Mycology LR12ES09, Faculty of Pharmacy, University of Monastir, Tunisia.
⁴ Department of Infectious Diseases, F. Bourguiba Teaching Hospital, University of Monastir, Monastir, Tunisia.
⁵ Laboratory of Cytology and Histopathology, F. Bourguiba Teaching Hospital, University of Monastir, Monastir, Tunisia.

Abstract

Kaposi's sarcoma is a well-known multifocal vascular tumor initially described by pathologist Moritz Kaposi. This report presents the case of a 38-year-old bisexual male who consulted the infectious diseases department with non-itchy maculopapular and purpuric lesions on the skin with the involvement of the oral mucosa, suggesting a diagnosis of Kaposi's sarcoma. Biological and radiological investigations were performed. The patient was found to be human immunodeficiency virus positive with a viral load of 251.000/mL and a CD4 count of 182/mm³. In addition, secondary syphilis was diagnosed. Histopathological examinations confirmed HHV-8 KS. The patient was treated with Extencilline^® and antiretroviral therapy. After 10 months of chemotherapy, a favorable outcome was noted with complete resolution of skin and oral mucosa lesions.

Keywords: HIV/AIDS; Kaposi sarcoma; outcome; syphilis; treatment.

Publication types

Case Reports