Pleomorphic carcinoma of the lung revealed by uncommon colonic metastasis: An exceptional case report with literature review

Asian Cardiovasc Thorac Ann. 2024 Mar 6:2184923241237315. doi: 10.1177/02184923241237315. Online ahead of print.

Abstract

Lung pleomorphic carcinoma is a rare and aggressive cancer that uncommonly metastasizes to the colon and only a few case reports have been published thus far. We present an exceptional case of colon metastasis from lung pleomorphic carcinoma in a 68-year-old man which was revealed by large bowel perforation, and we review the previous three published cases. Metastasis to the bowel from primary lung malignancy often lacks specific symptoms which result in delayed diagnosis. Bowel metastasis is a poor prognostic factor in patients with lung pleomorphic carcinoma, regardless of management strategy.

Keywords: Lung cancer; case report; colon metastasis; perforation; pleomorphic carcinoma.